Season 1 (Disc 2A): The Final Verdict
Scene: On the way to Claremont Bay (to find Marty Keene)
"... KITT, we can cut a hundred miles off this trip by
going through the desert. ..." 
BTW, Claremont Bay is actually San Pedro Bay in the real world.
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Season 1 (Disc 2B): The Topaz Connection 
Scene: On the way to Las Vegas!
http://www.youtube.com/watch?v=J4P9VBG4IfY" onclick="window.open(this.href);return false;
"KITT, plot me a route to Las Vegas off major highways."
Music: Traveling in a fried-out combie ... 'Land Down Under' by Men At Work
"... KITT, get me Devon ...
 ... Wonderful. I'll call you from Las Vegas.
 ... I got a plane to catch. ..."
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Top: KR scene, Bottom: same location today (paved road)
			
		
				
			
 
						- Vegas_route1.jpg (83.71 KiB) Viewed 46729 times
 
		
		
		
		
			 
Top: KR scene, Bottom: Bird's eye view (Virtual Earth)
One of the cue to this location is the gate in red circles.
			
		
				
			
 
						- Vegas_route2.jpg (128.28 KiB) Viewed 46728 times
 
		
		
		
		
			 
Coordinates: 34°28'12.22"N  117°38'35.45"W
Approx. address:
12121 Oasis Rd
Pinon Hills, CA 92372
(see street view on Google Maps !)
Comments:
I finally solve the mystery of the 'route to Las Vegas'.
The same scene first appeared in 'Final Verdict' where 
Michael cut thru the desert to save mileage.
The road is located in Mojave desert (off major highway 
I-15), between LA and Vegas, indeed! The runway where 
Michael and KITT took off is on Van Nuys Airport in the 
real world (see the image below). The distance between
the airport and the desert route location/Las Vegas is 
70/277 miles. Even if their speed was 300 miles/hour, 
was it possible to outrun the airplane? In real life, 
they have to get out of heavy traffic in LA first!
Route to Las Vegas:
A. Van Nuys Airport
C. desert route location
B. Las Vegas
			
		
				
			
 
						- Vegas_route3.jpg (88.5 KiB) Viewed 46722 times
 
		
		
		
		
			 
Van Nuys Airport:
http://www.lawa.org/vny/images/vnyphoto1.jpg" onclick="window.open(this.href);return false;